Singapore Lipidomics Incubator (SLING)

 

Background

Once viewed simply as a reservoir for carbon storage, lipids are no longer cast as bystanders in the drama of biological systems. The emerging field of lipidomics is driven by technology, most notably mass spectrometry, but also by complementary approaches for the characterization of lipids and their biosynthetic enzymes (Cell 2010,143,888).

SLING is a major global magnet for collaborating parties in lipidomics—from academia and industry—delivering new technologies and intellectual capital. Our centre offers cutting edge facilities and a diverse base of investigators and students, anchored at the National University of Singapore, a leading global University centered in Asia.

In recent years, lipidomics has emerged as a new scientific discipline with potential applications in pre-clinical and clinical research, well aligned with current research focus in Singapore. In this context, SLING brings together scientific collaborators, data scientists, biostatisticians, clinicians, and industrial partners via our unique model of engagement: the Hub for Translation and Capture.

SingMass@SLING is part of a National Mass Spectrometry Laboratory together with the NUS Protein and Proteomics Centre and the A*STAR Functional Proteomics Laboratory. SingMass aims at helping investigators in all steps of scientific endeavour, including experimental design, sample processing and data analysis.

Key Research Areas

  • Lipidomics workflows
  • Pre-clinical and clinical lipidomics
  • Natural Variations of lipids
  • Specific Research Area

  • Sphingolipids in health and disease
  • Lysophospholipids
  • Lipid transporters
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