Poh Chueh Loo
Associate Professor, Department of Biomedical Engineering
Faculty of Engineering
Tel: +65 6516 7657
Email: biepcl@nus.edu.sg

What are your present research interests?

My present research interests lie in synthetic biology, focusing on various foundational research including synthetic gene circuit design and automation, genetic sensors and optogenetics, modeling of biological systems and computer-aided design tools.

Do you have a distinctive viewpoint to your research?

Yes, my research team and I are very much motivated to make engineering of biology more efficient and predictive. We believe that the ability to scale complexity would greatly facilitate the creation of innovative biological solutions to many of the challenges the world faces today.

What do you see as your future research directions?

I want our research to continue to be driven with the goal of addressing healthcare and environmental challenges. Through the application of engineering principles on biological systems, we want to design and build microbes with useful capabilities for medical and industrial applications.

Does your laboratory have a particularly strong research expertise?

in our constant effort to accelerate the design and engineering of microbes, our laboratory has established competency in developing foundational platform tools in synthetic biology.

Recent Publications

1. Zhang J, Poh CL (2018) Regulating exopolysaccharide gene wcaF allows control of Escherichia coli biofilm formation. Scientific Reports, 8, 13127.
2. Jayaraman P, Yeoh JW, Jayaraman S, Teh AY, Zhang J, Poh CL (2018) Cell-Free Optogenetic Gene Expression System. ACS Synthetic Biology, 7(4): 986-994.
3. Ravikumar R, Chen LH, Jayaraman P, Poh CL, Chan CC (2018) Chitosan-nickel film based interferometric optical fiber sensor for label-free detection of histidine tagged proteins. Biosensors and Bioelectronics, 99: 578-585.
4. Jayaraman P, Devarajan K, Chua TK, Zhang H, Gunawan E, Poh CL (2016) Blue light-mediated transcriptional activation and repression of gene expression in bacteria. Nucleic Acids Research, 44(14): 6994-7005.